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Hypercalcemia with anorexia, nausea, weakness, weight loss, vague aches and stiffness, constipation, mental retardation, anemia, and mild acidosis.

The effects of administered vitamin D can persist for two or more months after cessation of treatment. 5 (tartrazine) sensitivity in the general population is low, it is frequently seen in patients who also have aspirin hypersensitivity.

Although the overall incidence of FD&C Yellow No. 5 (tartrazine) which may cause allergic-type reactions (including bronchial asthma) in certain susceptible individuals. Maintenance of a normal serum phosphorus level by dietary phosphate restriction and/or administration of aluminum gels as intestinal phosphate binders in those patients with hyperphosphatemia as frequently seen in renal osteodystrophy is essential to prevent metastatic calcification.Īdequate dietary calcium is necessary for clinical response to vitamin D therapy. In the treatment of hypoparathyroidism, intravenous calcium, parathyroid hormone, and/or dihydrotachysterol may be required. When high therapeutic doses are used progress should be followed with frequent blood calcium determinations.

IN VITAMIN D RESISTANT RICKETS THE RANGE BETWEEN THERAPEUTIC AND TOXIC DOSES IS NARROW. Dosage levels must be individualized and great care exercised to prevent serious toxic effects. Therapeutic dosage should be readjusted as soon as there is clinical improvement. Vitamin D administration from fortified foods, dietary supplements, self-administered and prescription drug sources should be evaluated. Inactive Ingredients: FD&C Blue #1, FD&C Yellow #5, Gelatin, Glycerin, Soybean Oil. One USP unit of vitamin D 2 is equivalent to one International Unit (IU), and 1 mcg of vitamin D 2 is equal to 40 IU.Įach capsule contains 1.25 mg (50,000 International Units vitamin D) of ergocalciferol, USP, in an edible vegetable oil.Įrgocalciferol, also called vitamin D 2, is 9, 10-secoergosta-5,7,10 (19), 22-tetraen-3-ol, (3ß,5Z,7E, 22 E)- (C 2 8H 4 4O) with a molecular weight of 396.65, and has the following structural formula: There are more than 10 substances belonging to a group of steroid compounds, classified as having vitamin D or antirachitic activity.

Ergosterol or provitamin D 2 is found in plants and yeast and has no antirachitic activity. DRISDOL brand of ergocalciferol capsules, USP, is a synthetic calcium regulator for oral administration.Įrgocalciferol is a white, colorless crystal, insoluble in water, soluble in organic solvents, and slightly soluble in vegetable oils.